Nucleic Acid Therapies – A Medicinal Revolution
Nucleic acid therapeutics are changing healthcare by offering transformative potential to treat diseases by targeting their genetic blueprints. Instead of treating symptoms, these therapies have the potential to address the disease root cause and potentially cure the previously incurable. Big investments are being made with Sweden emerging as a vibrant hotspot.
Addressing the disease root cause
After decades of intense research, nucleic acid therapeutics have now become increasingly common in clinics, with the mRNA COVID-19 vaccines as perhaps the most widely recognized example. These therapies utilize the building blocks of our genetic code, nucleic acids, that work inside the cells to affect the gene expression by inhibiting, adding, replacing or editing at DNA or RNA level. By doing so, nucleic acid therapeutics can achieve long-lasting or even curative effects.
“We used to think that our fate was in our stars, but now we know that, in large measure, our fate is in our genes”
- James Watson, Nobel price winner for discoveries regarding nucleic acids structure
The development of nucleic acid therapies is rapidly evolving driven by scientific breakthroughs and major investments in R&D activity. There are over 45 approved nucleic acid therapies worldwide to date and over 2 800 in development, addressing diseases such as various cancer types, Parkinson’s and Arthritis. In 2023, there are at least 10 new therapies that could be up for approval in US and Europe¹.
Usage of Generative AI in the Swedish Manufacturing Industry
Discover the untapped potential and key considerations of
deploying generative AI in the thriving Swedish manufacturing industry.
Deep dive into Triathlon's research which has summarized the advantages of,
as well as the risks associated with, this groundbreaking technology.
Through interviews with industry leaders, the report uncovers notable results
on the utilization and governance of generative AI. Explore the findings that
highlight the benefits of leveraging these innovative tools, while emphasizing
the critical importance of responsible and mindful implementation. After
reading this report, you will gain insight into the present-day landscape, the
vast potential of generative AI adoption, its accompanying risks and
actionable steps to ensure your organization is well-prepared for its
Emerging Transportation Management Systems
Emerging and disruptive technologies such as AI, Cloud Computing, Big Data Analytics, and Autonomous Vehicles have unlocked untapped potential for Transportation Management Systems (TMS), creating new opportunities to reshape the transport industry. This article elaborates on the enablers and features of next-generation TMS, enhancements compared to traditional TMS, how to succeed in implementing next-generation TMS, and future trends.
Enablers and features of next-generation TMS
TMS are logistics platforms streamlining processes of goods movement by connecting various data flows being analyzed and validated to make strategic and tactical changes. The immense increase of computing power and disruptive technology have enabled next-generation TMS to become remarkably fast and accurate compared to traditional TMS. Key enablers and features commonly associated with next-generation TMS are:
- Artificial Intelligence and Machine Learning – automating tasks by utilizing predictive analytics and dynamic routing
- Cloud Computing – offering the necessary infrastructure and scalability to enable real-time tracking and data sharing
- Big Data Analytics – processing GPS and telematics data to enhance route optimization and predictive maintenance
- Autonomous vehicles – optimizing transport by integrating and leveraging above listed enablers to improve resource utilization, minimizing downtime and delays
Capturing value in the energy transition
The rapidly increase of renewable energy sources paves the way for storage solutions. New regulatory and political incentives programs force actors in the industry to prepare for the new set-up to defend their industry space.
Renewables are now surpassing traditional sources
The global energy crisis has triggered unprecedented momentum behind renewables, with the world set to add as much renewable power in the next 5 years as it did in the past 20. That corresponds to additional 2,400 GW renewables installed, equivalent to China’s current total energy production. Renewables will, based on the two main drivers; cheaper renewables prices and global concerns about energy security, surpass coal and become the largest source of global electricity generation by 2025.
“Renewables will overtake coal as the largest source of electricity generation by 2025”
Intermitted sources drive the need of energy storage
Solar PV and wind power provide energy intermittently, so as the share of renewables increases in generation, volatility of the system will increase. To prevent more frequent mismatch of supply and demand balancing systems are expected to grow in parity of the renewables. One flexible and scalable solution is battery storage systems that can respond to sudden drops in renewable energy generation...
Democratizing Healthcare by Machine Learning
Machine learning is revolutionizing businesses, through valuable insights, predicted outcomes, and facilitated decision-making. In healthcare, the models efficiently analyze patient data, identify anomalies and offload staff. But besides a reliable algorithm are specific considerations, e.g., process adaptation, ethical aspects and continuous improvement. Despite these hurdles, machine learning is outlooked as a critical tool to democratize healthcare.
Succeeding in IT and Business Carve-Outs
Executing an IT separation within a business carve-out can be a daunting task for leadership teams. However, by considering the following points, the transformation can be executed with greater efficiency and clarity.
Co-opetition – Collaborate With Competitors to Get Ahead
Originating from game theory, co-opetition describes how competitors can cooperate to get ahead, or reach a common goal, by working together. Despite its benefits in the prevailing...
Assessing Environmental Impact With LCA
Organizations meet increased pressure to disclose their environmental impact. A Life Cycle Assessment (LCA) is a standardized methodology that quantifies this impact...
OKR – An Effective Tool to Drive Goal Achievement
Developed by Intel’s CEO Andy Grove back in the 1970’s, the goal and management method Objectives and Key Results (OKR) has since become the de facto methodology for many tech giants like Google, Amazon and Spotify and is spreading like wildfire across successful startups...
Supply Chain Resilience in a Market Downturn
The robust growth since the last global recession in 2008/2009 has reached its climax. We are now forced to face a stark new reality as a recession ominously looms in the not-so-distant future. It is hard to deny that the last two years have been challenging from a supply chain perspective, many were caught off-guard and supply chain inefficiencies were mercilessly punished...
Combining Data Privacy & Machine Learning
The development of computing capabilities during the last decades has enabled organizations to gather and process large amount of data using advanced machine learning techniques...
Gain Efficiencies by Product Variant Strategies
When companies extend offerings through product variants, they will face increasing costs and related challenges as the portfolio grows in complexity. Concurrently, variants generate deep customer value and justify higher price points, where mitigation strategies will enable improved lead times and profits gains...
Triathlon Group’s Industrial Report 2022/23
Triathlon Group’s annual Industrial Report (Verkstadsrapporten) shows that the Western Sweden’s manufacturing industry have recovered after the pandemic. However, high inflation, higher interest rates, continued material shortages and increasing energy prices result in that companies are uncertain about the future demand...
The M&A Year 2021 in Review and 2022 Outlook
M&A activity in Europe surged in 2021 with more capital spent on acquisitions than any of the previous seven years. After a relatively poor 2020, transaction volumes bounced back to pre-pandemic levels and more. Has the M&A market scaled new heights in Europe?
Making Industrial Facility Operations Sustainable
The industrial sector is a key driver of human-caused greenhouse gas emissions, and a significant share of these emissions comes from facility operations. As an example, natural gas is commonly used for space heating, contributing to carbon dioxide emissions...
Mandatory Human Rights and Environmental Due Diligence
The long-awaited proposal for an EU Directive on mandatory human rights and environmental due diligence has finally been released, following the increasing global momentum towards socially responsible and sustainable business. A topic that in times like these is ever more relevant.
The net-zero challenge for mobile machinery
Efforts in mitigating climate change have resulted in ambitious global targets on CO2 emission reductions. Highly affected by these targets are mobile machinery which now face a challenging transition towards net-zero emissions...
Navigating the regulatory space for MedTech AI
Artificial Intelligence (AI) holds unprecedented potential to transform how healthcare is delivered and will be vital to enable qualitative and cost-effective care in the future. However, the regulatory landscape for the intersection between healthcare and AI creates new challenges for innovators. Challenges that need to be successfully managed to launch new AI-medtech.
Healthcare needs AI to face tomorrow’s challenges
As the world population grows and life expectancy increases, healthcare needs technological advancements to be better equipped for future patients needs...
What is your contribution to Agenda 2030?
United Nations’ 17 Sustainability Development Goals (SDG) show the direction on how to make an impact on the world’s most urgent societal challenges. The...
Infection Control – mapping of strongholds in West Sweden
Following the increased concerns surrounding healthcare-associated infections, Infection prevention and control has become an increasingly more imp...
Get Topline Impact from Value-Driven Sales
Project sales between businesses are complex and to succeed with a high hit-rate, the sales process needs to turn from a traditional selling with ins...
Study on realization of ERP benefits
Expectations on a new ERP-system are often high. However, once the system goes live, studies show that most businesses experience unachieved realizations of ...
The M&A Year 2020 in Review
Heading into 2020, global M&A activity was declining, with both a deal value and deal count falling in 2019 compared to the all time high levels of ...